Hematological effects induced by programs of intermittent hypoxia
نویسندگان
چکیده
منابع مشابه
Intermittent Hypoxia-Induced Sensitization of Central Chemoreceptors
26 Hypertension elicited by chronic intermittent hypoxia (CIH) is associated with elevated 27 activity of the thoracic sympathetic nerve (tSN) that exhibits an enhanced respiratory modulation 28 reflecting a strengthened interaction between respiratory and sympathetic networks within the 29 brainstem. Expiration is a passive process except for special metabolic conditions as hypercapnia 30 when...
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Exposing rodents to brief episodes of hypoxia mimics the hypoxemia and the cardiovascular and metabolic effects observed in patients with obstructive sleep apnoea (OSA), a condition that affects between 5% and 20% of the population. Apart from daytime sleepiness, OSA is associated with a high incidence of systemic and pulmonary hypertension, peripheral vascular disease, stroke and sudden cardia...
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BACKGROUND Hypobaric intermittent hypoxia (HIH) produces many favorable effects in the cardiovascular system such as anti-hypertensive effect. In this study, we showed that HIH significantly attenuated a depressor response induced by acute hypoxia. METHODOLOGY/PRINCIPAL FINDINGS Sprague-Dawley rats received HIH in a hypobaric chamber simulating an altitude of 5000 m. The artery blood pressure...
متن کاملSympatho-adrenal activation by chronic intermittent hypoxia.
Recurrent apnea with chronic intermittent hypoxia (CIH) is a major clinical problem in adult humans and infants born preterm. Patients with recurrent apnea exhibit heightened sympathetic activity as well as elevated plasma catecholamine levels, and these phenotypes are effectively recapitulated in rodent models of CIH. This article summarizes findings from studies addressing sympathetic activat...
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The levels of serum inflammatory cytokines and the activation of nuclear factor kappa B (NF-κB) and hypoxia inducible factor-1α (HIF-1α) in heart tissues in response to different frequencies of intermittent hypoxia (IH) and the antioxidant tempol were evaluated. Wistar rats (64 males, 200-220 g) were randomly divided into 6 experimental groups and 2 control groups. Four groups were exposed to I...
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ژورنال
عنوان ژورنال: cultura_ciencia_deporte
سال: 2013
ISSN: 1696-5043,1989-7413
DOI: 10.12800/ccd.v8i24.362